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Carotid Plaque Composition by Magnetic Resonance Imaging During Lipid Lowering Therapy

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Trial Profile

Carotid Plaque Composition by Magnetic Resonance Imaging During Lipid Lowering Therapy

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 20 Feb 2024

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At a glance

  • Drugs Atorvastatin (Primary) ; Colesevelam (Primary) ; Niacin (Primary)
  • Indications Atherosclerosis
  • Focus Therapeutic Use
  • Acronyms CPC

    • Most Recent Events

    • 16 May 2022 Status changed from active, no longer recruiting to completed.
    • 16 May 2022 The primary outcome Changes in carotid plaque composition, as assessed by MRI was changed to Annualized LRNC Volume Change in Carotid Plaque Composition, as Assessed by MRI and Annualized LRNC and Wall Volume Changes in Carotid Plaque Composition, as Assessed by MRI, according to ClinicalTrials.gov record.
    • 01 Aug 2021 Results of a pooled analysis assessing the potential mechanisms for this lack of cardioprotection by quantifying the HDL proteome of subjects in 2 niacin clinical trials ( CPC study (Carotid Plaque Composition) and the HDL Proteomics substudy of the AIM-HIGH trial) published in the Arteriosclerosis Thrombosis and Vascular Biology

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