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A Phase II Trial of Oral Deforolimus (AP23573; MK-8669), an mTOR Inhibitor, in Combination With Trastuzumab for Patients With HER2-Positive Trastuzumab-Refractory Metastatic Breast Cancer

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Trial Profile

A Phase II Trial of Oral Deforolimus (AP23573; MK-8669), an mTOR Inhibitor, in Combination With Trastuzumab for Patients With HER2-Positive Trastuzumab-Refractory Metastatic Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 May 2022

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At a glance

  • Drugs Ridaforolimus (Primary) ; Trastuzumab
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Therapeutic Use
  • Sponsors ARIAD Pharmaceuticals; Merck & Co; Merck Sharp & Dohme

Most Recent Events

  • 24 Jul 2012 Planned number of patients changed from 37 to 66 as reported by European Clinical Trials Database record.
  • 23 Jun 2011 Actual end date (Mar 2011) added as reported by ClinicalTrials.gov.
  • 23 Jun 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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