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A Multinational, Multicenter, Randomized, Double-blind Study Comparing the Efficacy and Safety of Semuloparin (AVE5026) With Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Elective Knee Replacement Surgery

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A Multinational, Multicenter, Randomized, Double-blind Study Comparing the Efficacy and Safety of Semuloparin (AVE5026) With Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Elective Knee Replacement Surgery

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 02 Dec 2016

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At a glance

  • Drugs Semuloparin (Primary) ; Enoxaparin sodium
  • Indications Deep vein thrombosis; Pulmonary embolism; Thromboembolism
  • Focus Registrational; Therapeutic Use
  • Acronyms SAVE-KNEE
  • Sponsors Sanofi

    • Most Recent Events

    • 16 Mar 2012 Primary endpoint 'Venous-thromboembolism-event-rate' has not been met according to results published in the Journal of Thrombosis and Haemostasis.
    • 14 May 2010 actual patient number 1150 added, additional trial location (Greece, Romania) identified as reported by ClinicalTrials.gov.
    • 17 Jun 2009 Actual end date (May 2009) added as reported by ClinicalTrials.gov.

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