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Randomized study to assess the added value of Laromustine in combination with standard remission-induction chemotherapy in patients aged 18-65 years with previously untreated acute myeloid leukemia (AML) or myelodysplasia (MDS) (RAEB with IPSS greater than or equal to 1.5).

Trial Profile

Randomized study to assess the added value of Laromustine in combination with standard remission-induction chemotherapy in patients aged 18-65 years with previously untreated acute myeloid leukemia (AML) or myelodysplasia (MDS) (RAEB with IPSS greater than or equal to 1.5).

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 22 May 2014

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At a glance

  • Drugs Laromustine (Primary) ; Amsacrine; Cytarabine; Idarubicin
  • Indications Acute biphenotypic leukaemia; Acute myeloid leukaemia; Myelodysplastic syndromes; Refractory anaemia
  • Focus Registrational; Therapeutic Use
  • Acronyms HOVON-92-AML

Most Recent Events

  • 15 Mar 2012 This trial has been completed in Belgium and discontinued in Netherlands as reported by European Clinical Trials Database.
  • 15 Mar 2012 Actual initiation date (Sep 2008) added as reported by European Clinical Trials Database.
  • 15 Mar 2012 Planned End Date changed from 30 Sep 2012 to 12 Apr 2013 as reported by European Clinical Trials Database

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