Trial Profile

A Phase III Study of Microsomal Triglyceride Transfer Protein (MTP) Inhibitor AEGR-733 in Patients With Homozygous Familial Hypercholesterolemia on Current Lipid-Lowering Therapy.

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 29 Apr 2025

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At a glance

11 Apr 2025 Results assessing the effect of lomitapide on HDL and cholesterol efflux in a cohort of patients with HoF, published in the European Journal of Medical Research.
01 Feb 2023 Results assessing long-term hepatic safety of lomitapide from phase III clinical studies and extension study: NCT00730236, NCT00943306 and NCT02135705 published in the Liver International
01 Aug 2013 Lomitapide has been approved in Europe based on results from this trial according to an Aegerion Pharmaceuticals media release.

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