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A Double-Blind, Placebo-Controlled, Randomized, Multi-Center, Dose Finding Study of SLV320, a Selective A1 Adenosine Receptor Antagonist, to Evaluate the Effect on Renal Function and Safety in Subjects Hospitalized With Acute Decompensated Heart Failure and Renal Dysfunction (Reno-Defend 1).

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A Double-Blind, Placebo-Controlled, Randomized, Multi-Center, Dose Finding Study of SLV320, a Selective A1 Adenosine Receptor Antagonist, to Evaluate the Effect on Renal Function and Safety in Subjects Hospitalized With Acute Decompensated Heart Failure and Renal Dysfunction (Reno-Defend 1).

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 01 Apr 2022

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At a glance

  • Drugs SLV 320 (Primary)
  • Indications Decompensated heart failure
  • Focus Biomarker; Pharmacodynamics
  • Acronyms Reno-Defend-1
  • Sponsors Solvay

    • Most Recent Events

    • 01 Apr 2022 This trial has been completed in France (End Date: 4 Jan 2010) according to European Clinical Trials Database record.
    • 01 Jun 2011 Results published in American Heart Journal.
    • 18 Nov 2009 Actual number of patients (46) and actual end date (Dec 2009) added as reported by ClinicalTrials.gov.

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