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A randomized double blind phase III trial of Pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or following prior therapy (PALETTE)

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Trial Profile

A randomized double blind phase III trial of Pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or following prior therapy (PALETTE)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Sep 2023

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At a glance

  • Drugs Pazopanib (Primary)
  • Indications Leiomyosarcoma; Malignant fibrous histiocytoma; Soft tissue sarcoma; Synovial sarcoma
  • Focus Registrational; Therapeutic Use
  • Acronyms PALETTE
  • Sponsors GlaxoSmithKline; GlaxoSmithKline Research & Development; GSK
  • Most Recent Events

    • 05 Jun 2019 This trial has been completed in United Kingdom, according to European Clinical Trials Database.
    • 14 Feb 2019 Results evaluating coadministration of long term gastric acid suppressive agents therapy with pazopanib published in the Clinical Cancer Research
    • 12 Sep 2017 Results (n=333) of EORTC62043 and EORTC62072 trials assessing evolution in neutrophil to lymphocyte ratio in patients with advanced soft tissue sarcoma, presented at the 42nd European Society for Medical Oncology Congress.

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