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A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled Study to Investigate the Long-term Effects of Salmeterol/Fluticasone Propionate (Seretide tm) 50/500mcg BD, Salmeterol 50mcg BD and Fluticasone Propionate 500mcg BD, All Delivered Via the Diskus tm/Accuhaler tm Inhaler, on Mortality and Morbidity of Subjects With Chronic Obstructive Pulmonary Disease (COPD) Over 3 Years of Treatment

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Trial Profile

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled Study to Investigate the Long-term Effects of Salmeterol/Fluticasone Propionate (Seretide tm) 50/500mcg BD, Salmeterol 50mcg BD and Fluticasone Propionate 500mcg BD, All Delivered Via the Diskus tm/Accuhaler tm Inhaler, on Mortality and Morbidity of Subjects With Chronic Obstructive Pulmonary Disease (COPD) Over 3 Years of Treatment

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 18 Jul 2023

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At a glance

  • Drugs Salmeterol/fluticasone propionate (Primary) ; Fluticasone propionate; Salmeterol
  • Indications Chronic obstructive pulmonary disease
  • Focus Registrational; Therapeutic Use
  • Acronyms TORCH
  • Sponsors GlaxoSmithKline; GSK

Most Recent Events

  • 23 May 2018 Results presented at the 114th International Conference of the American Thoracic Society.
  • 24 May 2017 Results comparing patient characteristics from SLS COPD with SUMMIT, TORCH, FLAME and TRILOGY trials presented at the 113th International Conference of the American Thoracic Society
  • 01 Dec 2009 Effect of treatment on prevalence and progression of osteoporosis in a subset of US patients (n=658).

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