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A Multicenter, Randomized, Phase II Clinical Trial to Evaluate the Effect of Avastin in Combination With Neoadjuvant Treatment Regimens on the Molecular and Metabolic Characteristics and Changes in the Primary Tumors With Reference to the Obtained Responses in Patients With Large Primary HER2 Negative Breast Cancers

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Trial Profile

A Multicenter, Randomized, Phase II Clinical Trial to Evaluate the Effect of Avastin in Combination With Neoadjuvant Treatment Regimens on the Molecular and Metabolic Characteristics and Changes in the Primary Tumors With Reference to the Obtained Responses in Patients With Large Primary HER2 Negative Breast Cancers

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Mar 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Aromatase inhibitors; Cyclophosphamide; Docetaxel; Epirubicin; Fluorouracil; Paclitaxel
  • Indications Adenocarcinoma; Early breast cancer; HER2 negative breast cancer
  • Focus Therapeutic Use
  • Acronyms Neo-Ava; NeoAva
  • Sponsors Roche

    • Most Recent Events

    • 19 Oct 2023 Planned number of patients changed from 150 to 200.
    • 19 Apr 2023 Results deriving FFPE tissue sections from patients before, during, and after treatment , pursuing information on spatial organization of cellular phenotypes expressing selected cancer related proteins including our nine ViRP proteinspresented at the 114th Annual Meeting of the American Association for Cancer Research
    • 05 Jan 2023 Status changed from active, no longer recruiting to completed.
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