Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

A Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Prucalopride (R108512) Tablets in Subjects With Chronic Constipation

Next Previous
Search
Trial Profile

A Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Prucalopride (R108512) Tablets in Subjects With Chronic Constipation

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 22 Dec 2022

Price :
$35 *
Note:
  • Adis is an information provider.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
  • A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

  • Drugs Prucalopride (Primary)
  • Indications Constipation
  • Focus Registrational; Therapeutic Use
  • Sponsors Shire-Movetis NV

    • Most Recent Events

    • 26 Oct 2022 Results of post hoc pooled analysis from NCT01147926, NCT01424228, NCT01116206, NCT00483886,NCT0048594011 and NCT004881371; evaluating the effect of renal function on the efficacy and safety of prucalopride, presented at the American College of Gastroenterology Annual Scientific Meeting and Postgraduate Course 2022
    • 28 Oct 2020 Results of a post hoc analysis from NCT01147926; NCT00485940 ; NCT00483886; NCT00488137 and other studies assessing assess the effect of prucalopride on abdominal bloating, presented at the American College of Gastroenterology Annual Scientific Meeting and Postgraduate Course 2020
    • 17 Dec 2018 According to a Shire media release, the U.S. Food and Drug Administration (FDA) has approved Motegrity (prucalopride) once-daily oral treatment for adults with Chronic Idiopathic Constipation (CIC). The FDA has requested that Shire conduct five post-marketing studies evaluating the pharmacokinetics, efficacy, and safety of Motegrity in pediatric patients with CIC (6 months old to less than 18 years of age) and pregnant and lactating women with CIC treated with Motegrity.

You need to be a logged in or subscribed to view this content Request demo

If your organization or you do not have a subscription, try one of the following:
  • Contacting your organization’s admin about adding this content to your AdisInsight subscription
  • Buying a PDF version of any individual profile
  • Request a free trial
If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top