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A Phase I Efficacy and Safety Study of HPV16-Specific Therapeutic DNA-Vaccinia Vaccination in Combination With Topical Imiquimod, in Patients With HPV16+ High Grade Cervical Dysplasia (CIN3).

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Trial Profile

A Phase I Efficacy and Safety Study of HPV16-Specific Therapeutic DNA-Vaccinia Vaccination in Combination With Topical Imiquimod, in Patients With HPV16+ High Grade Cervical Dysplasia (CIN3).

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Human papillomavirus DNA vaccine (Primary) ; Human papillomavirus vaccine (Primary) ; Imiquimod (Primary)
  • Indications Cervical intraepithelial neoplasia; Human papillomavirus infections
  • Focus Adverse reactions; Pharmacodynamics; Therapeutic Use

Most Recent Events

  • 12 Jun 2020 Biomarkers information updated
  • 10 Jun 2013 Planned End Date changed from 1 Dec 2014 to 1 Dec 2015 as reported by ClinicalTrials.gov.
  • 12 Oct 2012 Planned number of patients changed from 36 to 48.

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