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A Randomised, 6-week, Multicentre, Open-label, Rater-blinded Parallel Group Study Comparing Quetiapine Extended Release Monotherapy and Augmentation With Lithium Augmentation in Patients With Treatment Resistant Depression.

Trial Profile

A Randomised, 6-week, Multicentre, Open-label, Rater-blinded Parallel Group Study Comparing Quetiapine Extended Release Monotherapy and Augmentation With Lithium Augmentation in Patients With Treatment Resistant Depression.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 29 Aug 2023

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At a glance

  • Drugs Quetiapine (Primary) ; Lithium; Serotonin uptake inhibitors; Venlafaxine
  • Indications Major depressive disorder
  • Focus Registrational; Therapeutic Use
  • Acronyms RUBY
  • Sponsors AstraZeneca
  • Most Recent Events

    • 26 May 2012 Company (GlaxoSmithKline) added to the associations field as reported by European Clinical Trials Database record.
    • 21 Apr 2012 Planned number of patients changed from 600 to 620 as reported by European Clinical Trials Database.
    • 28 Aug 2010 Results presented at the 23rd Annual Congress of the European College of Neuropsychopharmacology.

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