Trial Profile

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-Lowering Ezetimibe and the Non-Nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2.

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 18 Sep 2021

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At a glance

Drugs Efavirenz; Ezetimibe
Indications HIV-1 infections; Hypercholesterolaemia; Hyperlipoproteinaemia type II
Focus Pharmacokinetics

11 Oct 2010 Biomarkers information updated
04 Aug 2009 Actual end date (Jul 2009) added as reported by ClinicalTrials.gov.
04 Aug 2009 Status changed from not yet recruiting to completed as reported by ClinicalTrials.gov.

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