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Randomized, Double-Blind, Placebo-Controlled, Multi-Centre, Multi-National Study to Evaluate the Efficacy and Safety of Oral BAY63-2521 (1 mg, 1.5 mg, 2 mg, or 2.5 mg Tid) in Patients With Symptomatic Pulmonary Arterial Hypertension (PAH)

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Trial Profile

Randomized, Double-Blind, Placebo-Controlled, Multi-Centre, Multi-National Study to Evaluate the Efficacy and Safety of Oral BAY63-2521 (1 mg, 1.5 mg, 2 mg, or 2.5 mg Tid) in Patients With Symptomatic Pulmonary Arterial Hypertension (PAH)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Nov 2023

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At a glance

  • Drugs Riociguat (Primary)
  • Indications Pulmonary arterial hypertension
  • Focus Registrational; Therapeutic Use
  • Acronyms PATENT-1
  • Sponsors Bayer; Bayer HealthCare

Most Recent Events

  • 13 Nov 2023 Results of post-hoc analysis assessing COMPERA 2.0 to the PATENT 1& PATENT 2 studies of riociguat in patients with pulmonary arterial hypertension, presented at the American Heart Association Scientific Sessions 2023.
  • 13 Nov 2023 Results of pooled post hoc analysis (n=741 from studies PATENT-1, PATENT PLUS, RESPITE, MOTION, REPLACE) assessing the impact of riociguat in patients with PAH and comorbidities presented at the American Heart Association Scientific Sessions 2023
  • 28 Oct 2021 Results(n=396) from PATENT-1 and PATENT-2, investigating the effect of riociguat on REVEAL Lite 2 score, published in the Journal of Heart and Lung Transplantation

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