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A 52-Week, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Phase IIb Trial to Determine the Effects of Bardoxolone Methyl (RTA 402) on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease With an eGFR of 20 - 45 mL/Min/1.73m2.

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Trial Profile

A 52-Week, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Phase IIb Trial to Determine the Effects of Bardoxolone Methyl (RTA 402) on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease With an eGFR of 20 - 45 mL/Min/1.73m2.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Jun 2025

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At a glance

  • Drugs Bardoxolone methyl (Primary)
  • Indications Diabetic nephropathies
  • Focus Therapeutic Use
  • Acronyms BEAM
  • Sponsors Biogen; Reata Pharmaceuticals

Most Recent Events

  • 14 Nov 2016 Results published in the Reata Pharmaceuticals Media Release
  • 24 Jun 2011 Primary endpoint 'Glomerular-filtration-rate' has been met.
  • 24 Jun 2011 Results published in the New England Journal of Medicine.

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