Trial Profile

A Phase I Trial of Escalating Dose of RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS.

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 09 Apr 2026

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At a glance

Drugs Everolimus (Primary) ; Midostaurin (Primary)
Indications Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
Focus Adverse reactions

Most Recent Events

25 Mar 2026 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.
25 Mar 2026 Planned primary completion date changed from 1 Dec 2025 to 1 Dec 2026.
22 Jan 2024 Planned End Date changed from 1 Dec 2023 to 1 Dec 2025.

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