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NOPHO Treatment Protocol for Children (1.0 - 17.9 Years of Age) and Young Adults(18.0-45.0 Years) With Acute Lymphoblastic Leukemia. Intermittent Versus Continuous PEG-asparaginase for Asparagine Depletion.

Trial Profile

NOPHO Treatment Protocol for Children (1.0 - 17.9 Years of Age) and Young Adults(18.0-45.0 Years) With Acute Lymphoblastic Leukemia. Intermittent Versus Continuous PEG-asparaginase for Asparagine Depletion.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Jan 2022

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At a glance

  • Drugs Pegaspargase (Primary) ; Dexamethasone; Doxorubicin; Mercaptopurine; Methotrexate; Vincristine
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use
  • Most Recent Events

    • 21 Jun 2020 Results of an analysis from following clinical trials: Dutch: DCOG-ALL10/11 trials, Australian: ANZCHOG-ALL8 and AIEOP-BFM-ALL2009 trials, UK: ALL2003 trial and NOPHO-ALL2008 trial assessing association between Down syndrome and clinical outcome presented at the 25th Congress of the European Haematology Association
    • 01 Dec 2017 Results published in the Pediatric Blood and Cancer
    • 20 Apr 2017 Status changed from recruiting to completed.
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