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Phase II Study of Metastatic Melanoma Using a Chemoradiation Lymphodepleting Conditioning Regimen Followed by Infusion of Anti-Mart-1 and Anti-gp100 TCR-Gene Engineered Lymphocytes and Peptide Vaccines.

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Trial Profile

Phase II Study of Metastatic Melanoma Using a Chemoradiation Lymphodepleting Conditioning Regimen Followed by Infusion of Anti-Mart-1 and Anti-gp100 TCR-Gene Engineered Lymphocytes and Peptide Vaccines.

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Gp100-specific T lymphocyte therapy (Primary) ; MART-1-specific T lymphocyte therapy (Primary) ; Aldesleukin; Cyclophosphamide; Filgrastim; Fludarabine; Freund's adjuvant; Melanoma vaccine; Melanoma vaccine gp100; Montanide ISA-51
  • Indications Malignant melanoma
  • Focus Therapeutic Use

Most Recent Events

  • 28 Oct 2015 Biomarkers information updated
  • 23 Jul 2011 NCT00814684 states that the trial end date is Oct 2011.
  • 23 Jul 2011 NCT00814684 states that the trial end date is Oct 2011.

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