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A Double-Blind, Placebo-Controlled Study of Caripazine (RGH-188) As Adjunctive Therapy In Major Depressive Disorder

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Trial Profile

A Double-Blind, Placebo-Controlled Study of Caripazine (RGH-188) As Adjunctive Therapy In Major Depressive Disorder

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 09 Nov 2021

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At a glance

  • Drugs Cariprazine (Primary) ; Citalopram; Duloxetine; Escitalopram; Sertraline; Venlafaxine
  • Indications Major depressive disorder
  • Focus Therapeutic Use
  • Sponsors Forest Laboratories

    • Most Recent Events

    • 24 Jul 2018 Of 502 patients enrolled in the open-label period, 403 completed treatment and 172 were classified as responders. Of the 231 non responders who began double-blind treatment, according to results published in the International Clinical Psychopharmacology.
    • 24 Jul 2018 Primary endpoint (Montgomery-Asberg Depression Rating Scale(MADRS) changes (Assessed at week 16) has not been met, according to results published in the International Clinical Psychopharmacology.
    • 24 Jul 2018 Results (n=502) published in the International Clinical Psychopharmacology.

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