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A Multicenter Phase Ib Trial to Determine Whether a Gene Expression Signature Changes in Response to Treatment With Bcr-Abl Inhibitors in Patients With Blast Phase Philadelphia Chromosome Positive Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphocytic Leukemia.

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Trial Profile

A Multicenter Phase Ib Trial to Determine Whether a Gene Expression Signature Changes in Response to Treatment With Bcr-Abl Inhibitors in Patients With Blast Phase Philadelphia Chromosome Positive Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphocytic Leukemia.

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Dasatinib; Imatinib; Nilotinib
  • Indications Chronic myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Pharmacogenomic; Therapeutic Use

Most Recent Events

  • 30 Sep 2015 Biomarkers information updated
  • 07 Oct 2011 Status changed from completed to discontinued as reported by ClinicalTrials.gov.
  • 30 Jul 2010 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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