Trial Profile

Phase II Study of Rituximab in Combination With Methotrexate, Doxorubicin, Cyclophosphamide, Leucovorin, Vincristine, Ifosfamide, Etoposide, Cytarabine and Mesna (R-MACLO/IVAM) in Patients With Previously Untreated Mantle Cell Lymphoma

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 06 Aug 2025

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At a glance

Drugs Rituximab (Primary) ; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Filgrastim; Folinic acid; Ifosfamide; Mesna; Methotrexate; Vincristine
Indications Mantle-cell lymphoma
Focus Therapeutic Use

23 Jul 2025 Status changed from active, no longer recruiting to completed.
12 Aug 2021 Planned End Date changed from 1 Sep 2021 to 1 Sep 2027.
12 Aug 2021 Planned primary completion date changed from 1 Sep 2021 to 1 Sep 2024.

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