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A Phase 2 Study of Valproic Acid and Radiation, Followed by Maintenance Valproic Acid and Bevacizumab in Children With Newly Diagnosed High-Grade Gliomas or Brainstem Gliomas

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Trial Profile

A Phase 2 Study of Valproic Acid and Radiation, Followed by Maintenance Valproic Acid and Bevacizumab in Children With Newly Diagnosed High-Grade Gliomas or Brainstem Gliomas

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 09 Nov 2021

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At a glance

  • Drugs Bevacizumab (Primary) ; Valproic acid (Primary)
  • Indications Anaplastic astrocytoma; Glioblastoma; Glioma; Gliosarcoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 01 Jun 2020 Status changed from active, no longer recruiting to completed according to results published in the Pediatric Blood and Cancer.
    • 13 Jan 2020 Planned End Date changed from 1 May 2019 to 1 Jun 2020.
    • 13 Jan 2020 Planned primary completion date changed from 1 Sep 2018 to 1 Jun 2020.

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