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An open Phase II study to assess the clinical activity and safety of recMAGE-A3 + AS15 cancer immunotherapeutic in patients with metastatic cutaneous melanoma, and to explore its immunogenic properties, including their relation to tumor infiltration, genomics and proteomics.

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Trial Profile

An open Phase II study to assess the clinical activity and safety of recMAGE-A3 + AS15 cancer immunotherapeutic in patients with metastatic cutaneous melanoma, and to explore its immunogenic properties, including their relation to tumor infiltration, genomics and proteomics.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Sep 2023

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At a glance

  • Drugs Zastumotide (Primary)
  • Indications Malignant melanoma
  • Focus Adverse reactions; Pharmacodynamics; Pharmacogenomic; Therapeutic Use
  • Acronyms MAGE3-AS15-MEL-004 (MET); PREDICT
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 30 Dec 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
    • 12 Jul 2013 Planned end date changed from 1 Dec 2014 to 1 Nov 2014 as reported by ClinicalTrials.gov.
    • 14 Jan 2011 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.

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