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Effect of LY2062430, an Anti-Amyloid Beta Monoclonal Antibody, on the Progression of Alzheimer's Disease as Compared With Placebo

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Trial Profile

Effect of LY2062430, an Anti-Amyloid Beta Monoclonal Antibody, on the Progression of Alzheimer's Disease as Compared With Placebo

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 09 Nov 2021

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At a glance

  • Drugs Solanezumab (Primary)
  • Indications Alzheimer's disease
  • Focus Registrational; Therapeutic Use
  • Acronyms EXPEDITION-1
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 30 Jul 2021 Results from ENGAGE, EMERGE, Expedition 1, 2, and 3 and the PRIME study; combining evidence across outcomes and trials using bayesian hierarchical analysis, presented at the Alzheimer's Association International Conference 2021
    • 31 Jul 2020 Results of post hoc analysis from EXPEDITION-1 and EXPEDITION-2 presented at the Alzheimer's Association International Conference 2020
    • 20 Jul 2017 Results evaluating central drug target engagement (TE) and pharmacodynamic (PD) activity of solanezumab in EXPEDITION3 and comparing both to that in the pooled mild AD population from EXPEDITION and EXPEDITION 2 studies, presented at the Alzheimer's Association International Conference 2017

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