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A prospective, multi-center, randomized, double-blind trial to assess the effectiveness and safety of 12 versus 30 months of dual antiplatelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention (PCI) with either drug-eluting stent (DES) or bare metal stent (BMS) placement for the treatment of coronary artery lesions.

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A prospective, multi-center, randomized, double-blind trial to assess the effectiveness and safety of 12 versus 30 months of dual antiplatelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention (PCI) with either drug-eluting stent (DES) or bare metal stent (BMS) placement for the treatment of coronary artery lesions.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 20 Feb 2024

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At a glance

  • Drugs Clopidogrel (Primary) ; Prasugrel (Primary) ; Aspirin
  • Indications Coronary artery disease; Coronary stent thrombosis; Myocardial infarction; Stroke
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms DAPT

    • Most Recent Events

    • 26 Sep 2019 Results published in the American Journal of Cardiology.
    • 22 Feb 2017 Results (n=11648) assessing myocardial infarction risk after discontinuation of Thienopyridine in the randomized DAPT study, published in the Circulation.
    • 30 Aug 2016 Post hoc analysis (N=11643) published in the Circulation.

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