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A Randomised Phase III Study for Evaluating the Role of the Addition of Ovarian Function Suppression to Tamoxifen in Young Women With Hormone-Sensitive Breast Cancer Who Remain in Premenopause or Regain Menstruation After Chemotherapy

Trial Profile

A Randomised Phase III Study for Evaluating the Role of the Addition of Ovarian Function Suppression to Tamoxifen in Young Women With Hormone-Sensitive Breast Cancer Who Remain in Premenopause or Regain Menstruation After Chemotherapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 25 Nov 2024

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At a glance

  • Drugs Goserelin (Primary) ; Tamoxifen
  • Indications Adenocarcinoma; Advanced breast cancer; Early breast cancer
  • Focus Therapeutic Use
  • Acronyms ASTRRA

Most Recent Events

  • 05 Nov 2024 Results (n=957) assessing Prediction of menstrual recovery patterns in premenopausal women with breast cancer taking tamoxifen after chemotherapy published in the Breast Cancer Research
  • 22 Aug 2023 Results of a 8year follow up of the ASTRRA trial published in the Journal of Clinical Oncology.
  • 07 Jun 2022 Results (n=1293) of a retrospective analysis assessing mammographic breast density reduction rate and its impact on prognosis stratified by treatment presented at the 58th Annual Meeting of the American Society of Clinical Oncology

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