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A Phase II Randomized, Open-Label, Multicenter Study Comparing CO-1.01 With Gemcitabine as First-Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma

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Trial Profile

A Phase II Randomized, Open-Label, Multicenter Study Comparing CO-1.01 With Gemcitabine as First-Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Jan 2022

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At a glance

  • Drugs Gemcitabine elaidate (Primary) ; Gemcitabine
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms LEAP
  • Sponsors Clovis Oncology [CEASED]

    • Most Recent Events

    • 25 Jan 2020 Results assessing the patterns of opioid use, and evaluating the impact of opioid use on survival outcomes among patients with advanced GI cancers who were included in eight clinical trials (NCT01124786; NCT00844649; NCT00290966; NCT00678535; NCT00699374; NCT00272051; NCT00305188; NCT00384176) presented at the 2020 Gastrointestinal Cancers Symposium
    • 05 Jun 2018 Results of prognostic nomogram using training and validation cohorts from (NCT00844649, NCT01124786 and NCT00574275) presented at the 54th Annual Meeting of the American Society of Clinical Oncology
    • 20 Jan 2018 Results of pool data from the comparator arm of three clinical trails (NCT00844649, NCT01124786 and NCT00574275) in MPC treated with gemcitabine as first-line chemotherapy, were presented at the 2018 Gastrointestinal Cancers Symposium.

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