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A Randomized, Open-Label, Parallel-Group, Multiple-Dose Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-Administered in Healthy Subjects.

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A Randomized, Open-Label, Parallel-Group, Multiple-Dose Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-Administered in Healthy Subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Oct 2016

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At a glance

  • Drugs Bumetanide (Primary) ; Dapagliflozin (Primary)
  • Indications Heart failure; Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Sponsors AstraZeneca; Bristol-Myers Squibb

    • Most Recent Events

    • 18 Nov 2009 Planned number of patients changed from 648 to 24 as reported by ClinicalTrials.gov.
    • 07 Nov 2009 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 07 Nov 2009 Actual patient number (42) added as reported by ClinicalTrials.gov.

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