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PENTA18: A study of the pharmacokinetics, safety and efficacy of twice-daily versus once-daily lopinavir/ritonavir tablets dosed by weight as part of combination antiretroviral therapy in human immunodeficiency virus-1 (HIV-1) infected children.

Trial Profile

PENTA18: A study of the pharmacokinetics, safety and efficacy of twice-daily versus once-daily lopinavir/ritonavir tablets dosed by weight as part of combination antiretroviral therapy in human immunodeficiency virus-1 (HIV-1) infected children.

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 25 Jul 2022

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At a glance

  • Drugs Lopinavir/ritonavir (Primary) ; Antiretrovirals
  • Indications HIV-1 infections
  • Focus Pharmacokinetics; Therapeutic Use
  • Acronyms KONCERT; PENTA-18; PENTA18

Most Recent Events

  • 28 Nov 2015 Results published in the AIDS
  • 06 Mar 2014 Primary endpoint 'Viral-load' has not been met.
  • 06 Mar 2014 Results presented at the 21st Conference on Retroviruses and Opportunistic Infections.

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