Trial Profile
A Randomized Phase II Study of Two Dose-Levels of Vorinostat in Combination With 5-FU and Leucovorin in Patients With Refractory Metastatic Colorectal Cancer.
Status:
Completed
Phase of Trial:
Phase II
Latest Information Update: 11 May 2022
Price :
$35
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At a glance
- Drugs Vorinostat (Primary) ; Fluorouracil; Folinic acid
- Indications Adenocarcinoma; Colorectal cancer
- Focus Therapeutic Use
- 27 Mar 2012 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
- 27 Sep 2011 Results presented at the 2011 European Multidisciplinary Cancer Congress.
- 27 Sep 2011 Eight of 15 patients had disease control in the high-dose arm and the arm was closed to accrual; whereas, 9 of 15 patients had disease control in the low-dose arm and accrual was expanded to 43 patients.