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Randomized, Double-Blind, Placebo-Controlled, Multicenter, Exploratory Phase II Study to Compare Three Dose Regimens of GLPG0259 vs Placebo, in Combination With Methotrexate, Administered for 12 Weeks to Subjects With Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate.

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Trial Profile

Randomized, Double-Blind, Placebo-Controlled, Multicenter, Exploratory Phase II Study to Compare Three Dose Regimens of GLPG0259 vs Placebo, in Combination With Methotrexate, Administered for 12 Weeks to Subjects With Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate.

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 09 Nov 2021

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At a glance

  • Drugs GLPG 0259 (Primary)
  • Indications Rheumatoid arthritis
  • Focus Therapeutic Use

    • Most Recent Events

    • 09 Nov 2011 Interim results for the end of part A presented at the 75th Annual Scientific Meeting of the American College of Rheumatology and the 46th Annual Meeting of the Association of Rheumatology and Health Professionals.
    • 15 Apr 2011 Negative interim efficacy results reported in a Galapagos media release; however, no serious adverse events were reported.
    • 15 Apr 2011 Status changed from recruiting to discontinued due to the compound's limited efficacy potential, as reported in a Galapagos media release.
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