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A Phase Ib, Open-Label, Dose-Escalation Study of the Safety and Pharmacology of PI3-Kinase Inhibitor GDC-0941 (Pictilisib) in Combination With Paclitaxel, With and Without Bevacizumab or Trastuzumab, and With Letrozole in Patients With Locally Recurrent Or Metastatic Breast Cancer

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Trial Profile

A Phase Ib, Open-Label, Dose-Escalation Study of the Safety and Pharmacology of PI3-Kinase Inhibitor GDC-0941 (Pictilisib) in Combination With Paclitaxel, With and Without Bevacizumab or Trastuzumab, and With Letrozole in Patients With Locally Recurrent Or Metastatic Breast Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Jan 2020

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At a glance

  • Drugs Pictrelisib (Primary) ; Bevacizumab; Paclitaxel; Trastuzumab
  • Indications Adenocarcinoma; Advanced breast cancer
  • Focus Adverse reactions
  • Sponsors Genentech

Most Recent Events

  • 01 Jul 2016 Status changed from active, no longer recruiting to completed.
  • 21 Jan 2015 According to the ClinicalTrials.gov record, planned end date changed from 1 Aug 2015 to 1 Jan 2016.
  • 04 Jul 2014 Planned End Date changed from 1 Mar 2014 to 1 Aug 2015 as reported by ClinicalTrials.gov record.

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