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A Phase I/II Trial of Vorinostat (SAHA) (NSC-701852) in Combination With Rituximab-CHOP in Patients With Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL)

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Trial Profile

A Phase I/II Trial of Vorinostat (SAHA) (NSC-701852) in Combination With Rituximab-CHOP in Patients With Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL)

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 31 May 2026

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At a glance

  • Drugs Vorinostat (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Prednisone; Rituximab; Vincristine
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 28 Apr 2026 Planned End Date changed from 6 Mar 2026 to 6 Mar 2027.
  • 20 Mar 2025 Planned End Date changed from 7 Mar 2025 to 6 Mar 2026.
  • 08 Dec 2015 Results presented at the 57th Annual Meeting and Exposition of the American Society of Hematology

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