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An Exploratory Phase 2 Study to Assess the Effect of Dapagliflozin on Glomerular Filtration Rate (GFR) in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic and Blood Pressure (BP) Control.

Trial Profile

An Exploratory Phase 2 Study to Assess the Effect of Dapagliflozin on Glomerular Filtration Rate (GFR) in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic and Blood Pressure (BP) Control.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Mar 2017

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At a glance

  • Drugs Dapagliflozin (Primary) ; Hydrochlorothiazide
  • Indications Hypertension; Type 2 diabetes mellitus
  • Focus Pharmacodynamics
  • Sponsors AstraZeneca; Bristol-Myers Squibb
  • Most Recent Events

    • 01 Nov 2016 Results of a pooled post-hoc analysis of five phase IIb and 16 phase III studies (including this study) assessing frequency and characteristics of hypersensitivity adverse events, published in the Clinical Drug Investigation.
    • 24 Sep 2013 Results presented at the 49th Annual Meeting of the European Association for the Study of Diabetes.
    • 29 Aug 2012 Results presented at the ESC Congress 2012: Annual Congress of the European Society of Cardiology.
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