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Randomized Phase II Study of Pre-operative Chemoradiotherapy +/- Panitumumab (IND #110152) Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIA, N2+) Non-Small Cell Lung Cancer

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Trial Profile

Randomized Phase II Study of Pre-operative Chemoradiotherapy +/- Panitumumab (IND #110152) Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIA, N2+) Non-Small Cell Lung Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Jun 2022

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At a glance

  • Drugs Panitumumab (Primary) ; Carboplatin; Paclitaxel
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 01 Nov 2020 Results assessing early outcomes of anatomic resection following induction therapy with platinum-based chemotherapy and full-dose thoracic radiation for resectable N2+ stage IIIA non-small cell lung cancer from RTOG0229 and RTOG0839, published in the Journal of Thoracic and Cardiovascular Surgery.
    • 23 Aug 2016 NCT reports status "active, no longer recruiting" but according to results this study was completed, hence retained status as per results.
    • 07 Jun 2016 Primary endpoint (Mediastinal nodal clearance after completion of induction chemoradiotherapy with or without panitumumab) has not been met according to the results presented at the 52nd Annual Meeting of the American Society of Clinical Oncology.

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