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Pharmacokinetics of Plasma Lamivudine (3TC), and Its Active Intracellular Anabolite 3TC-Triphosphate Over a 24 Hour Dosing Interval Following Administration of 3TC 300 mg and 150 mg Once Daily to HIV-Negative Healthy Volunteers

Trial Profile

Pharmacokinetics of Plasma Lamivudine (3TC), and Its Active Intracellular Anabolite 3TC-Triphosphate Over a 24 Hour Dosing Interval Following Administration of 3TC 300 mg and 150 mg Once Daily to HIV-Negative Healthy Volunteers

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 24 Aug 2020

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At a glance

  • Drugs Lamivudine (Primary)
  • Indications HIV infections
  • Focus Pharmacokinetics
  • Acronyms ENCORE2

Most Recent Events

  • 20 Sep 2011 Primary endpoint 'Drug-concentration' has not been met.
  • 09 Feb 2011 Actual initiation date changed from 1 Sep 2009 to 1 Mar 2010 as reported by ClinicalTrials.gov.
  • 09 Feb 2011 Status changed from recruiting to completed as reported by ClinicalTrials.gov.

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