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A Phase 3 Study to Evaluate the Efficacy and Safety of Docetaxel and Prednisone With or Without Lenalidomide in Subjects With Castrate-Resistant Prostate Cancer (CRPC)

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Trial Profile

A Phase 3 Study to Evaluate the Efficacy and Safety of Docetaxel and Prednisone With or Without Lenalidomide in Subjects With Castrate-Resistant Prostate Cancer (CRPC)

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 09 Feb 2023

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At a glance

  • Drugs Lenalidomide (Primary) ; Docetaxel; Prednisone
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms MAINSAIL
  • Sponsors Celgene Corporation

    • Most Recent Events

    • 07 Jun 2022 Results (n=2028) from 4 randomized phase 3 trials (NCT00273338, NCT00988208, NCT00617669, and NCT00519285) presented at the 58th Annual Meeting of the American Society of Clinical Oncology
    • 21 Sep 2020 Results (n=1539) of MAINSAIL, ENTHUSE and VENICE trial assessing quality of life and survival in elderly metastatic castration-resistant prostate cancer presented at the 45th European Society for Medical Oncology Congress
    • 18 May 2020 Results (n=1577) of Ascent2, Mainsail and Venice trials, inverse correlation between obesity and mortality in patients, presented at the 115th Annual Meeting of the American Urological Association.

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