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Phase 2 Open-Label, AC220 Monotherapy Efficacy (ACE) Study in Patients With Acute Myeloid Leukemia (AML) With and Without FLT3-ITD Activating Mutations

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Trial Profile

Phase 2 Open-Label, AC220 Monotherapy Efficacy (ACE) Study in Patients With Acute Myeloid Leukemia (AML) With and Without FLT3-ITD Activating Mutations

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Feb 2024

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At a glance

  • Drugs Quizartinib (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms ACE
  • Sponsors Ambit Biosciences Corporation; Daiichi Sankyo Inc

    • Most Recent Events

    • 06 Nov 2019 Results of pooled data from four studies: one phase 3 (QuANTUM-R), two phase 2, (ACC220-002 and 2689-CL-2004), and one phase 1 (CP0001), released at the 61st Annual Meeting and Exposition of the American Society of Hematology.
    • 17 Jun 2018 Results of a post-hoc analysis from NCT01565668 and NCT00989261 studies presented at the 23rd Congress of the European Haematology Association.
    • 05 Jun 2018 Results of post hoc explopratory analysis of two phase 2 trials (NCT01565668; NCT00989261) presented at the 54th Annual Meeting of the American Society of Clinical Oncology

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