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A Phase I Study of Oral Sapacitabine and Oral Seliciclib in Patients With Advanced Solid Tumors

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Trial Profile

A Phase I Study of Oral Sapacitabine and Oral Seliciclib in Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 Dec 2021

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At a glance

  • Drugs Sapacitabine (Primary) ; Seliciclib (Primary)
  • Indications Advanced breast cancer; Ovarian cancer; Pancreatic cancer; Solid tumours
  • Focus Adverse reactions
  • Sponsors Cyclacel Pharmaceuticals
  • Most Recent Events

    • 07 Dec 2021 Status changed from recruiting to completed.
    • 03 Apr 2019 Results (n=20) from an expansion cohort assessing the safety and efficacy of oral sapacitabine and oral seliciclib regimen in patients with metastatic breast cancer and BRCA1/2 mutations presented at the 110th Annual Meeting of the American Association for Cancer Research
    • 05 Mar 2019 According to a Cyclacel Pharmaceuticals media release, data from expansion cohort of the study in patients with metastatic breast cancer and BRCA1/2 mutations, will be presented at the American Association for Cancer Research (AACR) Annual Meeting 2019.

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