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A Randomized, Double-blind, Placebo-controlled, Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CNTO 1959 Following a Single Intravenous or a Single Subcutaneous Administration in Healthy Subjects and in Subjects With Moderate to Severe Psoriasis.

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A Randomized, Double-blind, Placebo-controlled, Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CNTO 1959 Following a Single Intravenous or a Single Subcutaneous Administration in Healthy Subjects and in Subjects With Moderate to Severe Psoriasis.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 16 Jul 2018

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At a glance

  • Drugs Guselkumab (Primary) ; Guselkumab (Primary)
  • Indications Psoriasis
  • Focus Adverse reactions; First in man
  • Sponsors Centocor; Janssen Biotech

    • Most Recent Events

    • 16 Jun 2018 Results evaluating Cellular and Molecular Changes in response to selective Il-23 Blockade vs Dual Il-12/23 blockade in Psoriasis Skin presented at the 19th Annual Congress of the European League Against Rheumatism.
    • 12 Mar 2016 Results (n = 64) presented at the 117th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics.
    • 04 Nov 2010 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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