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A randomized, double-blind, placebo controlled, multi-centre phase IIb dose finding study to assess the effect on GERD symptoms, safety and tolerability during four weeks treatment with AZD3355 in doses 60 mg, 120 mg, 180 mg and 240 mg bid as add-on treatment to a PPI in patients with GERD that are partial responders to PPI treatment

Trial Profile

A randomized, double-blind, placebo controlled, multi-centre phase IIb dose finding study to assess the effect on GERD symptoms, safety and tolerability during four weeks treatment with AZD3355 in doses 60 mg, 120 mg, 180 mg and 240 mg bid as add-on treatment to a PPI in patients with GERD that are partial responders to PPI treatment

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Oct 2021

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At a glance

  • Drugs Lesogaberan (Primary) ; Proton pump inhibitors
  • Indications Gastro-oesophageal reflux
  • Focus Therapeutic Use
  • Sponsors AstraZeneca
  • Most Recent Events

    • 03 Jul 2012 Additional trial locations (Germany, Latvia, Hungary and France) added as reported by European Clinical Trials Database record.
    • 26 Oct 2011 Results presented at the 19th United European Gastroenterology Week.
    • 10 May 2011 Tolerability results presented at Digestive Disease Week 2011.
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