A Phase II Randomized Clinical Trial Evaluating Neoadjuvant Therapy Regimens with Weekly Paclitaxel plus Neratinib or Trastuzumab or Neratinib and Trastuzumab Followed by Doxorubicin and Cyclophosphamide with Postoperative Trastuzumab in Women with Locally Advanced HER2 Positive Breast Cancer.

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 24 Dec 2021

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At a glance

Drugs Neratinib (Primary) ; Cyclophosphamide; Doxorubicin; Paclitaxel; Trastuzumab
Indications Adenocarcinoma; Advanced breast cancer; Early breast cancer; HER2 positive breast cancer
Focus Therapeutic Use
Sponsors NSABP Foundation

Most Recent Events

31 Jul 2018 Status changed from active, no longer recruiting to completed.
03 Mar 2017 This trial is completed in Portugal. (End date: 25 Nov 2016)
19 Dec 2016 This trial has been completed in Spain

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