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An Open-label, Randomized, Controlled, Multicenter, Phase I/II Trial Investigating 2 EMD 525797 Doses in Combination With Cetuximab and Irinotecan Versus Cetuximab and Irinotecan Alone, as Second-line Treatment for Subjects With K-ras Wild Type Metastatic Colorectal Cancer (mCRC)

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Trial Profile

An Open-label, Randomized, Controlled, Multicenter, Phase I/II Trial Investigating 2 EMD 525797 Doses in Combination With Cetuximab and Irinotecan Versus Cetuximab and Irinotecan Alone, as Second-line Treatment for Subjects With K-ras Wild Type Metastatic Colorectal Cancer (mCRC)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Abituzumab (Primary) ; Cetuximab; Irinotecan
  • Indications Carcinoma; Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms POSEIDON
  • Sponsors Merck KGaA; Merck Sharp & Dohme

Most Recent Events

  • 08 Oct 2018 According to a Merck KGaA media release, data from this study will be presented at the European Society for Medical Oncology Annual Meeting (ESMO) 2018 Congress.
  • 29 Mar 2016 Number of treatment arms changed from 3 to 7, as reported by ClinicalTrials.gov record.
  • 29 Mar 2016 Status changed from discontinued to completed, according to ClinicalTrials.gov record.

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