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Phase III Randomized Trial of Clofarabine as Induction and Post-Remission Therapy vs. Standard Daunorubicin and Cytarabine Induction and Intermediate Dose Cytarabine Post-Remission Therapy, Followed by Decitabine Maintenance vs. Observation in Newly-Diagnosed Acute Myeloid Leukemia in Older Adults (Age greater than or equal to 60 Years)

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Phase III Randomized Trial of Clofarabine as Induction and Post-Remission Therapy vs. Standard Daunorubicin and Cytarabine Induction and Intermediate Dose Cytarabine Post-Remission Therapy, Followed by Decitabine Maintenance vs. Observation in Newly-Diagnosed Acute Myeloid Leukemia in Older Adults (Age greater than or equal to 60 Years)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Dec 2024

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At a glance

  • Drugs Clofarabine (Primary) ; Cytarabine; Daunorubicin; Fludarabine
  • Indications Acute myeloid leukaemia; Graft-versus-host disease
  • Focus Therapeutic Use
  • Acronyms ECOG-ACRIN E2906

    • Most Recent Events

    • 13 Dec 2024 Status changed from active, no longer recruiting to completed.
    • 13 Dec 2024 Status changed from active, no longer recruiting to completed.
    • 12 Dec 2023 Results of prospective patient-reported outcomes (PRO) assessment of HRQoL and fatigue to understand treatment impact from the patients(pts) perspective, presented at the 65th American Society of Hematology Annual Meeting and Exposition

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