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A Single-centre, Randomised, Double-blind, Placebo-controlled, Four-period Cross-over Study to Evaluate the Scopolamine Cognition Model in Healthy Male Subjects Using AZD1446 and Donepezil Versus Placebo.

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Trial Profile

A Single-centre, Randomised, Double-blind, Placebo-controlled, Four-period Cross-over Study to Evaluate the Scopolamine Cognition Model in Healthy Male Subjects Using AZD1446 and Donepezil Versus Placebo.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs AZD 1446 (Primary) ; Donepezil
  • Indications Cognition disorders
  • Focus Pharmacodynamics

Most Recent Events

  • 08 Oct 2010 Primary endpoint 'EEG changes' has not been met.
  • 12 Feb 2010 Completion is expected in the second half of 2010, according to a Targacept media release.
  • 14 Jan 2010 New trial record

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