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An Open-label, Multi-center, One Sequence Cross-over Drug Interaction Study to Investigate the Effect of Tocilizumab (TCZ, RO4877533) on the Pharmacokinetics and Pharmacodynamics of an Oral Contraceptive (OC) in Female Patients With Active Rheumatoid Arthritis (RA)

Trial Profile

An Open-label, Multi-center, One Sequence Cross-over Drug Interaction Study to Investigate the Effect of Tocilizumab (TCZ, RO4877533) on the Pharmacokinetics and Pharmacodynamics of an Oral Contraceptive (OC) in Female Patients With Active Rheumatoid Arthritis (RA)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Tocilizumab (Primary) ; Ethinylestradiol/norethisterone
  • Indications Rheumatoid arthritis
  • Focus Pharmacodynamics
  • Sponsors Roche

Most Recent Events

  • 17 Jul 2012 Actual patient number changed from 45 to 46 according to ClinicalTrials.gov.
  • 06 Jul 2012 Actual patient number changed from 44 to 45 according to ClinicalTrials.gov.
  • 16 Mar 2012 Actual patient number added 44 according to ClinicalTrials.gov.

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