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A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas

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Trial Profile

A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Jul 2025

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At a glance

  • Drugs Indimitecan (Primary) ; Indotecan (Primary)
  • Indications Adenocarcinoma; Adrenocortical carcinoma; Bladder cancer; Breast cancer; Colorectal cancer; Head and neck cancer; Hodgkin's disease; Lymphoma; Male breast cancer; Malignant melanoma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Parotid cancer; Renal cell carcinoma; Sarcoma; Small cell lung cancer; Solid tumours; Thyroid cancer; Vulvovaginal cancer
  • Focus Adverse reactions; First in man

Most Recent Events

  • 22 Jun 2017 Status changed from active, no longer recruiting to completed.
  • 22 Jun 2017 Status changed from active, no longer recruiting to completed.
  • 02 Jun 2017 Results (n=34) assessing safety and tolerability of LMP776 in patients with with relapsed solid tumors and lymphomas, presented at the 53rd Annual Meeting of the American Society of Clinical Oncology.

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