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A Confirmatory Multicenter, Single-arm Study to Assess the Efficacy, Safety, and Tolerability of the BiTE Antibody Blinatumomab in Adult Patients With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (BLAST)

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A Confirmatory Multicenter, Single-arm Study to Assess the Efficacy, Safety, and Tolerability of the BiTE Antibody Blinatumomab in Adult Patients With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (BLAST)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 15 Jul 2024

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At a glance

  • Drugs Blinatumomab (Primary)
  • Indications Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms BLAST
  • Sponsors Amgen

    • Most Recent Events

    • 20 May 2020 Results assessing patient failure-time data from the BLAST trial and a historical comparator study to evaluate cost-effectiveness of blinatumomab versus chemotherapy, presented at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research
    • 20 May 2020 Results presented at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research
    • 06 Nov 2019 Results assessing safety and efficacy of Blinatumomab in patients with B-Cell Acute Lymphoblastic Leukemia and Positive Measurable Residual Disease, released in the 61st Annual Meeting and Exposition of the American Society of Hematology

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