Randomized Treatment Interruption of Natalizumab.

Trial Profile

Randomized Treatment Interruption of Natalizumab.

Phase of Trial: Phase II

Latest Information Update: 15 Sep 2017

At a glance

  • Drugs Natalizumab (Primary) ; Glatiramer acetate; Interferon beta-1a; Methylprednisolone
  • Indications Multiple sclerosis
  • Focus Therapeutic Use
  • Acronyms RESTORE
  • Sponsors Biogen
  • Most Recent Events

    • 15 Sep 2017 Results assessing reversibility of natalizumab-mediated changes in pharmacokinetics/pharmacodynamics using patient data from AFFIRM and RESTORE trials published in the Neurology
    • 17 Sep 2016 Results of this and other four trials assessing relationship of natalizumab exposure and MRI response presented at the 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis
    • 28 Mar 2014 Results published in the Neurology.
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