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AIPAC (Active Immunotherapy PAClitaxel): A Multicentre, Phase IIb, Randomised,Double Blind, Placebo-controlled Study in Hormone Receptor-positive Metastatic Breast Carcinoma Patients Receiving IMP321 (LAG-3Ig Fusion Protein) or Placebo as Adjunctive to a Standard Chemotherapy Treatment Regimen of Paclitaxel

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Trial Profile

AIPAC (Active Immunotherapy PAClitaxel): A Multicentre, Phase IIb, Randomised,Double Blind, Placebo-controlled Study in Hormone Receptor-positive Metastatic Breast Carcinoma Patients Receiving IMP321 (LAG-3Ig Fusion Protein) or Placebo as Adjunctive to a Standard Chemotherapy Treatment Regimen of Paclitaxel

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Nov 2023

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At a glance

  • Drugs Eftilagimod alpha (Primary) ; Paclitaxel
  • Indications Adenocarcinoma; Advanced breast cancer; HER2 negative breast cancer
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms AIPAC
  • Sponsors Immutep

    • Most Recent Events

    • 08 Nov 2023 Primary endpoint has not been met. (Assessment of Progression-Free Survival (PFS))
    • 08 Nov 2023 Results published in the Clinical Cancer Research
    • 04 May 2022 According to an Immutep Limited media release, new biomarker and multivariate analysis data from this study was presented at the ESMO's Breast Cancer Congress 2022
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